Insulin/Insulin-Like Growth Factor-1 Signaling and Cognitive Function in Humans
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چکیده
منابع مشابه
Insulin/Insulin-like growth factor-1 signaling and cognitive function in humans.
An accumulating body of evidence suggests the involvement of an evolutionary conserved insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS) pathway in the regulation of the life and health span in nematodes, flies, rodents, and humans. We studied the association between insulin/IGF-1 signaling and cognitive function among 1015 participants, 85 years old or older, of the population-based...
متن کاملInsulin-like growth factor and cognitive function.
tive outcome of full-term small for gestational age infants at late adolescence. Obstet Gynecol 1995;85:452-6. 12 Fawer CL, Besnier S, Forcada M, Buclin T, Calame A. Influence of perinatal, developmental and environmental factors on cognitive abilities of preterm children without major impairments at 5 years. Early Hum Dev 1995;43:151-64. 13 Illsley R, Mitchell RG, eds. Low birth weight: a medi...
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The zinc element (Zn) is one of the micronutrients and an essential element of the body which has some deleterious and irreparable effects on growth in case of lack it. Thus, we aimed to assess IGF-1 in goldfish with Zn deficiency and to investigate the effect of Zn supplementation on these parameters. Goldfish (Carassius auratus) juvenile (3.5 g) were fed purified diets based on casein as ...
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Insulin-like growth factor (IGF)-1 is implicated in learning and memory. Experimental studies have suggested that the IGF-1 system is beneficial in cognition, especially in Alzheimer's disease (AD), by opposing Aβ amyloid processing and hyperphosphorylated tau toxicity. Low IGF-I and insulin-like growth factor binding protein (IGFBP)-3 serum levels are significantly associated with AD. To asses...
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Background & Objective: To find an association between gene variants of insulin-like growth factor-1 (IGF-1) and 5,10-methylenetetrahydrofolate reductase (MTHFR) with the risk of acne vulgaris (AV). Methods: In a case-control study, we investigated 150 AV patients and 148 healthy individuals (aged 18-25 years) for the IGF-1 G>A and MTHFR C677T polymorphis...
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ژورنال
عنوان ژورنال: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
سال: 2008
ISSN: 1079-5006,1758-535X
DOI: 10.1093/gerona/63.9.907